Zhou, W., Woodson, M., Neupane, B., Bai, F., Sherman, M.B., Choi, K.H., Neelakanta, G., Sultana, H # (2018). Exosomes serve as novel modes of tick-borne flavivirus transmission from arthropod to human cells and facilitates dissemination of viral RNA and proteins to the vertebrate neuronal cells. PLoS Pathogens ;14(1):e1006764. Epub 2018/01/05. doi: 10.1371/journal.ppat.1006764. PubMed PMID: 29300779.​ First author is a shared PhD student with Dr. Neelakanta; ​ #Corresponding author

  1. This work is considered as “Featured article” by PLOS Pathogens- Editors-in-Chief (http://journals.plos.org/plospathogens/)​
  2. This work has been highlighted by PLOS Pathogens in the EurekAlert (the Global Source for Science News). Please see the relevant website https://www.eurekalert.org/pub_releases/2018-01/p-tem122817.php
  3. This work is been highlighted by Science Daily https://www.sciencedaily.com/releases/2018/01/180104153522.htm
  4. This work is been highlighted by Genetic Engineering and Biotechnology News (https://www.genengnews.com/?utm_medium=newsletter)​


Dutta, S., Huddleston, A., Khanal, S., Simms, C., Arca, J.F., Mitra, A., Heller, L., Kraj, P.J., Ledizet, M., Anderson, J.F., Neelakanta, G., Holder, A.A., and Sultana, H # (2017). Coordination of different complexes to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes. Biochim Biophys Acta. 2017 Oct 10. pii: S0304-4165(17)30325-2. doi: 10.1016/j.bbagen.2017.10.004. ‡ First author is my PhD student, Authors 2-5 are PhD graduate or undergraduate students; ​#Corresponding author

Taank, V., Dutta, S., Dasgupta, A., Steeves, T.K., Fish, D., Anderson, J.F., Sultana, H., and Neelakanta, G # (2017). Human rickettsial pathogen modulates arthropod organic anion transporting polypeptide and tryptophan pathway for its survival in ticks. Scientific Reports (Nature Press). Oct 16;7(1):13256. doi: 10.1038/s41598-017-13559-x. ( First and second authors are PhD graduate students)

Neelakanta, G. # , Sultana, H., Sonenshine, D.E., and Andersen, J.F (2017). Identification and characterization of a histamine-binding lipocalin-like molecule from the relapsing fever tick Ornithodoros turicata. Insect Mol. Bio. 10.1111/imb.12362

Khanal, S., Sultana, H, Catravas, J.D., Carlyon, J.A., and Neelakanta, G # (2017). Anaplasma phagocytophilum infection modulates expression of megakaryocyte cell cycle genes through phosphatidylinositol-3-kinase signaling. PLoS One 12(8):e0182898. ( First author is PhD graduate student)​


Neelakanta, G., and Sultana, H#. Viral receptors of the gut: Vector-borne viruses of medical importance. Current Opinion in Insect Science (Vectors and Medical and Veterinary Entomology section 2016). Invited Review, #Co-corresponding authors

Sultana, H, Examination of West Nile virus Neuroinvasion and Neuropathogenesis in the Central Nervous System of a murine model. Methods in Molecular Biology (MiMB), West Nile Virus, vol. xxx, Springer Press. Invited book chapter contribution, ​#Corresponding author, [Book Chapter]

Sultana, H, Patel, U., Toliver, M., Maggi, R.G., and Neelakanta, G. Molecular Identification and bioinformatics analysis of a potential anti-vector vaccine candidate, 15 kDa salivary gland protein (Salp15), homologues from Ixodes affinis ticks. Ticks and Tick Borne Diseases. 2016 Feb;7(1):46-53. Second author is my undergraduate student


Sultana, H, Patel, U., Sonenshine, D. E., and Neelakanta, G. Identification and Comparative analysis of Subolesin/akirin ortholog from Ornithodoros turicata ticks. Parasites & vectors. 2015 Feb 28;8:132. Second author is my undergraduate student

Neelakanta, G., and Sultana, H#. 2014. Transmission-Blocking Vaccines: Focus on Anti-Vector Vaccines against Tick-Borne Diseases. Arch Immunol Ther Exp (Warsz). 2015 Jun;63(3):169-79. Invited Review, #Co-corresponding authors


Sultana, H. Pan-Flavivirus Vaccine(s): Are we there yet? J Multidiscip Pathol. 2014 1(1):1-5. # Invited Editorial Board Commentary

Sultana, H., and Neelakanta, G. 2014. Vector-borne diseases. In: Diseases and Theranostics, Biotechnology (multi-volume set), Ed: J.N.Govil, Studium Press LLC, U.S.A 9:241-270. [Book Chapter].

Neelakanta, G., and Sultana, H#. Bacterial, Protozoan and Viral Life-Threatening Diseases. In: Diseases and Theranostics, Biotechnology (multi-volume set), Ed: J.N.Govil, Studium Press LLC, U.S.A 2014 9:271-289. # Corresponding author, [Book Chapter].

Heisig, M$., Abraham, N.M$., Liu, L$., Neelakanta, G$., Mattessich, S., Sultana, H., Shang, Z., Ansari, J.M., Killiam, C., Walker, W., et al. 2014. Antivirulence properties of an antifreeze protein. Cell Rep. 2014 9:417-424. $ EQUAL FIRST AUTHOR

This article was highlighted in:
Yale News article, Oct 16, 2014 with the title “Tick protein does the trick to fight infection


Neelakanta, G., and Sultana, H#. The Use of Metagenomic Approaches to Analyze Changes in Microbial Communities. Microbiology Insights 2013 Apr 16;6:37-48. Invited Review, # Corresponding author


Sultana, H#., Neelakanta, G., Foellmer, H.G., Montgomery, R.R., Anderson, J.F., Koski, R.A., Medzhitov, R.M., and Fikrig, E. Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-beta1/Smad6 signaling. J Immunol 2012 Sep 15;189(6):3150-8. # Corresponding author

Neelakanta, G., Hudson, A.M., Sultana, H., Cooley, L., and Fikrig, E. Expression of Ixodes scapularis antifreeze glycoprotein enhances cold tolerance in Drosophila melanogaster. PLoS One 2012;7(3):e33447.

Sultana, H#., Neelakanta, G., Rivero, F., Blau-Wasser, R., Schleicher, M., and Noegel, A.A. Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells. BMC Dev Biol 2012 Jan 12;12:3. # Corresponding author


Sultana, H $., Neelakanta, G $., Kantor, F.S., Malawista, S.E., Fish, D., Montgomery, R.R., and Fikrig, E. Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks. J Exp Med. 2010 207:1727-1743. $ EQUAL FIRST AUTHOR

Neelakanta, G., Sultana, H., Fish, D., Anderson, J.F., and Fikrig, E. Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold. J Clin Invest. 2010 Sep;120(9):3179-90. Selected as one of the Science Editor’s choice articles: Science 329, 1442. Commentary published in J Clin Invest 120(9): 3087-3090

This article was highlighted as:

  1. Editor choice article in “Science”. 329, 1442​
  2. Research highlight article in “Nature Reviews Microbiology” Vol. 8, 2010,
  3. Commentary article in J Clin Invest 120: 3087-90.
  4. Research highlighted in Oxford Journal-Clinical Infectious Diseases

Wang, P$., Arjona, A$., Zhang, Y., Sultana, H, Dai, J., Yang, L., LeBlanc, P. M., Doiron, K., Saleh, M., and Fikrig, E. Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I. Nat Immunol. 2010 Oct;11(10):912-9. $ EQUAL AUTHOR CONTRIBUTION


Sultana, H., Foellmer, H.G., Neelakanta, G., Oliphant, T., Engle, M., Ledizet, M., Krishnan, M.N., Bonafe, N., Anthony, K.G., Marasco, W.A., et al. Fusion loop peptide of the West Nile virus envelope protein is essential for pathogenesis and is recognized by a therapeutic cross-reactive human monoclonal antibody. J Immunol 2009 Jul 1;183(1):650-60. Evaluation of this article is published in Future Virology (2009), Vol. 4, Pages 419-422.

This article was highlighted as:

  1. “Towards a broadly active Flavivirus therapeutic antibody” Future virology. Vol. 4 No. 5, Pages 419-422 (Priority Paper Evaluation in Future ​Medicine
  2. ​Highlighted in review articles “Possible future Monoclonal Antibody-based Therapy against arbovirus infections” and Antibody mediated ​neutralization of Flaviviruses: A reductionist view​
  3. Highlighted in CDC Stacks (stacks.cdc.gov/view/cdc/8126/cdc_8126_DS17.txt)​

Sultana, H., Neelakanta, G., Eichinger, L., Rivero, F., and Noegel, A.A. Microarray phenotyping places cyclase associated protein CAP at the crossroad of signaling pathways reorganizing the actin cytoskeleton in Dictyostelium. Exp Cell Res 2009 Jan 15;315(2):127-40.


Krishnan, M.N., Ng, A., Sukumaran, B., Gilfoy, F.D., Uchil, P.D., Sultana, H., Brass, A.L., Adametz, R., Tsui, M., Qian, F., Montogomery, R.R., Lev, S., Mason, P.W., Koski, R, A., Elledge, S.J., Xavier, R.J., Agaisse, H., and Fikrig, E. RNA interference screen for human genes associated with West Nile virus infection. Nature 2008 Sep 11;455(7210):242-5


Sultana, H, and Koleske, A. J. Regulation of Neuronal Morphogenesis by Abl Family Kinases. In Intracellular Mechanisms for Neuritogenesis, I. de Curtis, ed. (Springer US), 2007 pp. 180-194. [BOOK Chapter]


Sultana, H, Rivero, F., Blau-Wasser, R., Schwager, S., Balbo, A., Bozzaro, S., Schleicher, M., and Noegel, A. A. Cyclase-associated protein is essential for the functioning of the endo-lysosomal system and provides a link to the actin cytoskeleton. Traffic 2005 Oct;6(10):930-46.


Noegel, A. A., Blau-Wasser, R., Sultana, H, Muller, R., Israel, L., Schleicher, M., Patel, H., and Weijer, C. J. The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in Dictyostelium. Mol Biol Cell 2004 Feb;15(2):934-45.